Addressing the effects of chronic pain

 Neuropsychological Profiling of High-Impact Spinal Cord Injury Neuropathic Pain with Thermal Quantitative Sensory Testing and Endogenous Pain Control Biomarkers (DOLSCI I)

Need: The DolSCI Network investigating neuropathic pain control following spinal cord injury.

In the UK, approximately 40,000 people are living with spinal cord injury. An estimated two-thirds of these, over 25,000, people are living with neuropathic (chronic) pain, which has an enormous impact on psychological wellbeing and quality of life.

Chronic pain is a major complication following spinal cord injury.  It is constant , can be felt in many different places and can lead to depression, sleeplessness, anger and frustration and isolation.

Despite recent advances in our understanding of how non-invasive brain modulation or electroencephalographic (EEG) feedback m ay control neuropathic  pain after spinal cord injury, little is known how these therapeutic strategies may control specific high-impact pain phenotypes, normal endogenous pain control and reducing maladaptive and adaptive coping strategies.

The DoISCI Network co-ordinated and managed by Dr Bethel Osuagwu will combine national and international expertise to assess the effect of established research protocols for the non-invasive magnetic stimulation and EEG neurofeedback feedback of affected pain centres on both resting and pain-evoked activity within these areas.

Project Stage:  Ongoing

Location: National Spinal Injuries Centre, Stoke Mandeville; University of Buckingham

Project Manager: Dr Bethel Osuagwu (Masson Clinical Research Fellow)

Research Team:

Dr Imogen Cotter (Clinical Psychologist, NSIC)

Mr Maurizio Belci (Spinal Consultant, NSIC)

Dr Alex Nowicky, Brunel University

Vanessa Mutzel (University of Buckingham)

Dr Katherine Finlay (Chartered Psychologist, University of Buckingham)

Dr Julian Taylor, (Paraplegic Hospital of Toledo)


Funding: Multiple sources





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